Protein profile of Brazilian Pythium insidiosum isolates
نویسندگان
چکیده
منابع مشابه
Enzymatic variability among Brazilian Pythium insidiosum isolates.
BACKGROUND Pythium insidiosum is an oomycete classified in the kingdom Stramenopila. P. insidiosum hyphae are not able to initiate infection without the secretion of hydrolytic enzymes, which are considered an important factor in microbial virulence. AIMS To evaluate the extracellular enzymatic activity of 14 Brazilian P. insidiosum isolates and a standard strain (ATCC 58637) by the API-ZYM S...
متن کاملPythium insidiosum: an overview.
Pythium insidiosum is an oomycete pathogenic in mammals. The infection occurs mainly in tropical and subtropical areas, particularly in horses, dogs and humans. Infection is acquired through small wounds via contact with water that contains motile zoospores or other propagules (zoospores or hyphae). The disease, though described as emerging has in fact already been described since 1884. Dependi...
متن کاملA molecular phylogeny of Pythium insidiosum.
Sequence analysis of the ribosomal DNA internal transcribed spacers (ITS) was used to establish phylogenetic relationships among 23 isolates of Pythium insidiosum, the etiological agent of pythiosis in mammals. The isolates were divided into three distinct clades that exhibited significant geographic isolation. Clade I consisted of isolates from North, Central, and South America, while clade II...
متن کاملIn vitro susceptibility of Pythium insidiosum isolates to aminoglycoside antibiotics and tigecycline.
This study evaluated the in vitro activity of aminoglycoside antibiotics and tigecycline against Pythium insidiosum. The susceptibility tests were carried out using the broth microdilution method in accordance with the CLSI document M38-A2. MIC values for gentamicin, neomycin, paromomycin, and streptomycin ranged from 32 to 64 mg/liter, and the minimal fungicidal concentration (MFC) ranged from...
متن کاملCaspofungin in vitro and in vivo activity against Brazilian Pythium insidiosum strains isolated from animals.
OBJECTIVES The present study evaluated the susceptibility of 27 clinical isolates of Pythium insidiosum to caspofungin in vitro and correlated the results with the therapeutic response in vivo in rabbits with experimental pythiosis. METHODS The macrodilution method was performed in accordance with the CLSI document M38-A technique. Three reading criteria for MICs were adopted: MIC0, MIC1 and ...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2017
ISSN: 1369-3786,1460-2709
DOI: 10.1093/mmy/myx071